Aug 7, 2023 · Anticonvulsants, or antiepileptics, are an ever-growing class of medications that act through multiple different mechanisms to control seizures — antiepileptic toxicity commonly presents with a triad of symptoms, which includes central nervous system (CNS) depression, ataxia, and nystagmus
A patient who ingested a dose of TOPAMAX ® between 96 and 110 g was admitted to a hospital with a coma lasting 20 to 24 hours followed by full recovery after 3 to 4 days
In acute topiramate overdose, the most frequent clinical features reported are drowsiness, vertigo, agitation, and
Symptoms of toxicity include sedation, speech disturbance, blurred vision, agitation
We reviewed the medical records of two patients who took a topiramate overdose as a suicide attempt
Additionally, we provide a review of literature on all reported cases of topiramate toxicity
Abstract Due to the diverse mechanisms of action of antiseizure drugs, there has been a rise in prescriptions of these drugs for non-epileptic pathologies
Addiction treatment: Treatment for teens is inaccessible, costly as U
Portugal cut drug deaths by 80%, using free health care and addiction treatment
Data Synthesis There is compelling evidence for the
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The cost of acute treatment for topiramate-treated patients was about $27 less than the cost estimate for untreated patients
It is taken orally (by mouth)
2003;361 Long-term follow-up of patients after an intensive treatment program is recommended
In clinical trials involving children ages 12 years and older who took Topamax for migraine, the most common side effects were: feeling of pins and needles or tingling
The purpose of this article is to review demographic characteristics, clinical features, and management options of TiAAC
It is approved for the treatment of seizures (epilepsy) in adults and children in combination with other anticonvulsants and for preventing migraine headaches in adults
Topiramate (Topamax, CAS nr 97240-79-4) is an anticonvulsant agent indicated as adjunct therapy for the treatment of partial seizures, Seven cases of acute and acute-on-chronic topiramate toxicity observed in two clinical units of Polish Poison Control Centers in 2004–2005 were analyzed
The classic onset of topiramate-induced angle closure occurs shortly after starting the drug
per dose 25 mg) for 1 week, dose to be taken at night, then increased in steps of 0
If the results are abnormal, the
These are generally less toxic in overdose causing sedation and non-specific neurological symptoms and patients do well with supportive care