Subsequent complications include bone marrow suppression with resultant leukopenia, thrombocytopenia (nadir in 4-7 general feeling of illness
8 mg/kg is considered a lethal dose of colchicine, fatal cases of patients who followed a critical disease course after an intake below this lethal dose have been reported
Among drug intoxications, high doses of colchicine ingestion can lead to rapid multiorgan dysfunction, and patients with a severe overdose can experience
This condition is caused by too much uric acid in the blood
The use of colchicine is limited by its toxicity, 1 and colchicine overdose is associated with a high mortality rate
A 56-year-old man with a clear history of colchicine overdose was admitted to our hospital nearly 40 hours after taking 12 mg (0
Colchicine toxicity may be fatal
Therapy is
17 mg/kg) of colchicine
Objective: To report a case of colchicine intoxication occurring with institution of clarithromycin
Accidental overdose of insufflated colchicine
The use of colchicine is limited by its toxicity, 1 and colchicine overdose is associated with a high mortality rate
Abstract
The B
While a deliberate overdose of colchicine may be fatal in up to 10% of cases, 15w judicious use of colchicine at doses of 0
The most common symptoms were nausea and vomiting observed in 19 (90
3%) had died, the cause being disseminated intravascular coagulation (DIC) in two cases and severe
5-0
Dans tous les cas, la mesure des concentrations plasmatiques de colchicine a permis de confirmer l’intoxication à la colchicine
To our knowledge, this is the first
The clinical features associated with overdose and the options for treatment are discussed
Colchicine is used to prevent gout attacks (sudden, severe pain in one or more joints caused by abnormally high levels of a substance called uric acid in the blood) in adults
The intoxication severity and mortality are directly depending on the ingested dose
Colchicine intoxication is a rare but potentially life-threatening event
Acute intoxication with colchicine is uncommon but often severe and results in multiple visceral organ dysfunctions