• Triple Therapy (7-10 days) Clarithromycin 500 mg twice daily together with amoxicillin 1000 mg twice daily and omeprazole 20 mg once daily for 7-10 days
Extended release formulations are also available
For oral dosage forms (suspension and tablets): Adults—250 to 500 milligrams (mg)
Acute Maxillary Sinusitis
Tablet Extended Release 24 Hour, Oral: Generic: 500 mg Pharmacology Mechanism of Action Exerts its antibacterial action by binding to 50S ribosomal subunit
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The recommended adult dose of the extended-release form of clarithromycin is 1,000 mg (2 tablets) once daily for 5 to 14 days, depending on the condition being treated
The dosage may be increased to 1000 mg daily in more severe infections
Indicated treatment and prophylaxis of mycobacterial infections
Clarithromycin should be administered with oral omeprazole 40 mg once daily
When used with other medications to kill H
Trial 1 enrolled 154 adult patients and trial 2 enrolled 469 adult patients
As modified-release tab: 500 mg once daily, may be increased to 1,000 Clarithromycin - Get up-to-date information on Clarithromycin side effects, uses, dosage, overdose, pregnancy, alcohol and more
Find out how clarithromycin treats chest infections and pneumonia, and how to take it
Omeprazole 40 mg daily was given in combination with clarithromycin 500 mg every 8 hours to healthy adult male subjects
The trials were designed to evaluate the Clarithromycin 500 mg twice daily together with a proton pump inhibitor at the recommended daily dose and metronidazole 400 mg twice daily for 7 days
500 mg once daily usually for 7–14 days, increased to 1 g
Renal impairment
5 mg twice daily for 5 days
The American Thoracic Society and Infectious Disease Society of America cite a study that suggests tolerated dosages of 25 mg/kg three times weekly for both drugs
The safety and efficacy of 500 mg clarithromycin in patients with severe renal impairment has not been established
Consider clarithromcycin dose reduction in patients with renal impairment
The dosage need not be decreased for moderate to severe hepatic failure in the presence of normal renal function
It also is used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection [a type of lung infection that often In adult HIV-infected patients taking 500- or 1000-mg doses of clarithromycin every 12 hours, steady-state clarithromycin C max values ranged from 2 to 4 mcg/mL and 5 to 10 mcg/mL, Following administration of fluconazole 200 mg daily and clarithromycin 500 mg twice daily to 21 healthy volunteers,